#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games

Jul 23, 2025 · 2h 34m

About this episode

Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI. Thank you for listening ❤ Check out our sponsors: <a href="https://lexfridman.com/sponsors/ep475-sc">https://lexfridman.com/sponsors/ep475-sc</a> See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: <a href="https://lexfridman.com/demis-hassabis-2-transcript">https://lexfridman.com/demis-hassabis-2-transcript</a> CONTACT LEX: Feedback – give feedback to Lex: <a href="https://lexfridman.com/survey">https://lexfridman.com/survey</a> AMA – submit questions, videos or call-in: <a href="https://lexfridman.com/ama">https://lexfridman.com/ama</a> Hiring – join our team: <a href="https://lexfridman.com/hiring">https://lexfridman.com/hiring</a> Other – other ways to get in touch: <a href="https://lexfridman.com/contact">https://lexfridman.com/contact</a> EPISODE LINKS: Demis’s X: <a href="https://x.com/demishassabis">https://x.com/demishassabis</a> DeepMind’s X: <a href="https://x.com/GoogleDeepMind">https://x.com/GoogleDeepMind</a> DeepMind’s Instagram: <a href="https://instagram.com/GoogleDeepMind">https://instagram.com/GoogleDeepMind</a> DeepMind’s Website: <a href="https://deepmind.google/">https://deepmind.google/</a> Gemini’s Website: <a href="https://gemini.google.com/">https://gemini.google.com/</a> Isomorphic Labs: <a href="https://isomorphiclabs.com/">https://isomorphiclabs.com/</a> The MANIAC (book): <a href="https://amzn.to/4lOXJ81">https://amzn.to/4lOXJ81</a> Life Ascending (book): <a href="https://amzn.to/3AhUP7z">https://amzn.to/3AhUP7z</a> SPONSORS: To support this podcast, check out our sponsors & get discounts: Hampton: Community for high-growth founders and CEOs. Go to <a href="https://lexfridman.com/s/hampton-ep475-sc">https://joinhampton.com/lex</a> Fin: AI agent for customer service. Go to <a href="https://lexfridman.com/s/fin-ep475-sc">https://fin.ai/lex</a> Shopify: Sell stuff online. Go to <a href="https://lexfridman.com/s/shopify-ep475-sc">https://shopify.com/lex</a> LMNT: Zero-sugar electrolyte drink mix. Go to <a href="https://lexfridman.com/s/lmnt-ep475-sc">https://drinkLMNT.com/lex</a> AG1: All-in-one daily nutrition drink. Go to <a href="https://lexfridman.com/s/ag1-ep475-sc">https://drinkag1.com/lex</a> OUTLINE: (00:00) – Introduction (00:29) – Sponsors, Comments, and Reflections (08:40) – Learnable patterns in nature (12:22) – Computation and P vs NP (21:00) – Veo 3 and understanding reality (25:24) – Video games (37:26) – AlphaEvolve (43:27) – AI research (47:51) – Simulating a biological organism (52:34) – Origin of life (58:49) – Path to AGI (1:09:35) – Scaling laws (1:12:51) – Compute (1:15:38) – Future of energy (1:19:34) – Human nature (1:24:28) – Google and the race to AGI (1:42:27) – Competition and AI talent (1:49:01) – Future of programming (1:55:27) – John von Neumann (2:04:41) – p(doom) (2:09:24) – Humanity (2:12:30) – Consciousness and quantum computation (2:18:40) – David Foster Wallace (2:25:54) – Education and research PODCAST LINKS: – Podcast Website: <a href="https://lexfridman.com/podcast">https://lexfridman.com/podcast</a> – Apple Podcasts: <a href="https://apple.co/2lwqZIr">https://apple.co/2lwqZIr</a> – Spotify: <a href="https://spoti.fi/2nEwCF8">https://spoti.fi/2nEwCF8</a> – RSS: <a href="https://lexfridman.com/feed/podcast/">https://lexfridman.com/feed/podcast/</a> – Podcast Playlist: <a href="https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4">https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4</a> – Clips Channel: <a href="https://www.youtube.com/lexclips">https://www.youtube.com/lexclips</a>